Galvanotropism and "reversal of Inhibition" by Strychnine

نویسنده

  • W. J. Crozier
چکیده

The cathodically galvanotropic orientation of nemerteans, Lineus, and the anodic orientation of the gephyrean Echiurus, are reversed by the action of strychnine under conditions such that the typical "reversal of inhibition" induced by this substance is apparent. Nicotine does not give this result. Since it is necessary to assume that the strychnine effect is due to action upon the central ganglia, and since the galvanotropic effect depends upon action of the current on nerve cell bodies of the central ganglia, it must be assumed that the locus of reversal by strychnine is not perikaryal, but presumably synaptic.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

On Reversal of Geotropism in Asterina

A certain level of strychninization induces in Asterina reversal of geotropism from the normally geonegative movement to a persistent downward creeping. The effect of an attached float producing upward pull is to induce upward creeping, under these conditions, whereas normally it leads to downward movement. This reversal cannot be regarded as due to a mere intensification of the sensory effect ...

متن کامل

Reversal of Reaction by Means of Strychnine in Planarians and Starfish

Two cases have been described, that of the marine planarian Bdelloura and that of the starfish Asterias forbesii, in which strychnine reverses reciprocal inhibition. These facts indicate that the nervous systems of these invertebrates function in a manner similar to those of the earthworm and vertebrates. Moreover, it would seem that strychnine acts upon some chemical component of the neuron wh...

متن کامل

Death Due to Strychnine Poisoning in a Health Worker’s Suicide: A Case Report

Introduction: Strychnine is a natural alkaloid, which is used as pesticide for many years. In this report, a case of suicide with Strychnine was presented. Patient Information: In a suicide scene, a 55-year-old male health worker was found with spastic and arched back spine and rigid muscles similar to rigor mortis. In autopsy, signs of superficial burning were seen in the mucous membranes of m...

متن کامل

RNAi Induced Inhibition of MRP1 Expression and Reversal of Drug Resistance in Human Promyelocytic HL60 Cell Line

Multidrug resistance (MDR) is a complex phenomenon in which many different genes regulating drug transport, cellular repair, detoxification and drug metabolism are involved. Nevertheless, in most drug resistant cell lines and cancer patients up-regulation of ABC-transporter genes such as MDR associated Protein (MRP1) gene could be at the basis of the drug resistance phenotype. We aimed to decre...

متن کامل

The Analysis of Neuromuscular Mechanisms in Chiton

1. The degree of curvature of the body and of the girdle of a Chiton is determined by the activity of antagonistic muscle groups. At a certain, early stage in the strychninization of a Chiton the reciprocal inhibition involved in the natural use of these muscle groups is reversed, such that extensor muscles, rather than, as normally, flexor muscles, contract as the result of stimulation. This c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of General Physiology

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2003